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1000L Cell Culture Multi-stages Stainless steel Biofermenter

Microbial Stainless steel fermentation Microbial Stainless steel parallel fermenter Microbial Stainless steel parallel Bio reactor Microbial fermenter Microbial/cell culture SS fermenter Microbial/cell culture SS Bioreactor

500L Multi-parallel Stainless steel Biofermenter
1. In-situ sterilization, safe and reliable.
2. No traditional leakage risk;
3. Multiple reliable inoculation methods, flame inoculation and pressure differential inoculation are available;
4. Reasonable structural design, beautiful appearance;

Microbial Stainless steel fermentation Microbial Stainless steel parallel fermenter Microbial Stainless steel parallel Bio reactor Microbial fermenter Microbial/cell culture SS fermenter Microbial/cell culture SS Bioreactor

    Parameter

    Description Cell Culture Multi-stages Stainless steel Biofermenter

    Total volume

    5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 50KL etc.

    Working volume

    30%~70%

    Tank

    Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of
    diameter and height is 1:2.2-2.5

    Stirring system

    Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle
    Stir speed: 50~1000rpm/50-400rpm

    Sterilization

    Sterilize in place(SIP), auto control by program

    Clean

    Clean in place (CIP) by spray ball

    Gas control

    Control by rotor meter, air flow 1 vvm

    Feeding

    Automatically feeding by peristaltic pump

    Anti-foam control

    Automatically add antifoam by peristaltic pump

    Temperature control

    Auto-control, electric heating range: water source add 5℃ to 70℃


  • Parameters

    Parameter

    Description Cell Culture Multi-stages Stainless steel Biofermenter

    Total volume

    5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 50KL etc.

    Working volume

    30%~70%

    Tank

    Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of
    diameter and height is 1:2.2-2.5

    Stirring system

    Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle
    Stir speed: 50~1000rpm/50-400rpm

    Sterilization

    Sterilize in place(SIP), auto control by program

    Clean

    Clean in place (CIP) by spray ball

    Gas control

    Control by rotor meter, air flow 1 vvm

    Feeding

    Automatically feeding by peristaltic pump

    Anti-foam control

    Automatically add antifoam by peristaltic pump

    Temperature control

    Auto-control, electric heating range: water source add 5℃ to 70℃


1000L Cell Culture Multi-stages Stainless steel Biofermenter

Introduction of Cell Culture Multi-stages Stainless steel Biofermenter

Multi-parallel Bioreactors system normally consists of 2-16 sets, which applicated for Multimodal comparison test of Microorganism culture fermentation, optimization of fermentation process parameters, and verification of production process and related species. It can save much time and labor cost.
With complete functions and high degree of automation, it can be widely used in medicine, food industry, biological and chemical industry, agriculture, brewing and other industries. The equipment design and manufacturing meet the requirements of GMP.

 

Equipment features of  Cell Culture Multi-stages Stainless steel Biofermenter:

1. In-situ sterilization, safe and reliable.

2. No traditional leakage risk;

3. Multiple reliable inoculation methods, flame inoculation and pressure differential inoculation are available;

4. Reasonable structural design, beautiful appearance;

 

Features of Controlling System

Multiple Control Function

Associated control: temperature, stirring speed, pH, dissolved oxygen, defoaming, airflow, tank pressure, feed amount and other direct parameters.

Remote monitoring: Suitable for smartphones, tablets, laptops and PC for instant remote monitoring.

Step control: Users can switch directly between manual control and step control and set at least 10-step control program for temperature, agitation, PH, DO and feeding.

 

Smart PID control

Temperature, stirring speed, Ph, DO and other parameters in the tank can be controlled by subsection curve setting according to the process requirements.

Temperature Control: Adopt PID automatic control mode; SS316L jacket base for electric heating and cold water for cooling.

Dissolved oxygen control: equipped with DO electrode and shielded conductor, DO is associated with stirring motor speed, feeding, airflow, tank pressure and other parameters.

PH value control: Intelligent PID system control built-in control peristaltic pumps for acid-alkali adjustment, with high control precision.

Antifoam control: Foams are automatically detected and the peristaltic pump is controlled to add defoamer in proportion to time.

Feeding control: Peristaltic pump switch control (manual, automatic, and off); accumulation volume control; coupled with other parameters (DO, pH, etc).

 


Upgrading option list Cell Culture Multi-stages Stainless steel Biofermenter

Gas mixing options: Air/O2/CO2/N2

Cleanliness detection

Online live cell detectio

Automatic vessel pressure control

Top areation

Thermal mass flow controller

CO2 detection

Redox

Exhaust detection analysis

Liquid level

Filling weighing system

Methanol and ethanol content online detection

Additional feed pump

Variable speed pump

Upper controller

Magnetic drive

Customizable blade

Vessel passivation

Custom port
Cover lifting

 

Parameter of Cell Culture Multi-stages Stainless steel Biofermenter:

 

Parameter

Description

Total volume

5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 50KL etc.

Working volume

30%~70%

Tank

Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of
diameter and height is 1:2.2-2.5

Stirring system

Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle
Stir speed: 50~1000rpm/50-400rpm

Sterilization

Sterilize in place(SIP), auto control by program

Clean

Clean in place (CIP) by spray ball

Gas control

Control by rotor meter, air flow 1 vvm

Feeding

Automatically feeding by peristaltic pump

Anti-foam control

Automatically add antifoam by peristaltic pump

Temperature control

Auto-control, electric heating range: water source add 5℃ to 70℃

PH control

PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland.

Do control

0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

Sampling

Sampling valve, can sterilization separately, manual

Harvest

Zero dead zone bottom valve(Gemu/Burket,Germany), can sterilization separately, manual/auto

Lid lift system

30L-500L have lid lift system, 700-1000L have human hole.

Pressure

Auto control, BD Germany pressure transmitter

Exhaust

Have condenser before exhaust, control by diagram valve / Proportional control valve.

Control parameters

10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data
analysis, data record, data output, language(RU/EN/CN) and other customized functions

Optional configuration

Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas flow 2vvm, gas(CO2) exhaust analysis, Level sensor,
Turbidity(OD) sensor, ORP sensor, Weight system, Live cell sensor(Biomass), Printing, Siemens touch screen, Double mechanical seal
, 4-Valves-group for feeding, Bottom valve auto discharge, ASME certificate, CSA certificate, Batch culture, Seed transfer, etc.

 



1000L Cell Culture Multi-stages Stainless steel Biofermenter
500L Multi-parallel Stainless steel Biofermenter
1. In-situ sterilization, safe and reliable.
2. No traditional leakage risk;
3. Multiple reliable inoculation methods, flame inoculation and pressure differential inoculation are available;
4. Reasonable structural design, beautiful appearance;
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XI'AN RICH SMART TECHNOLOGY CO.,LTD

 Address: Zhangba East Road, Yanta District, Xi’an, China.China
Tel: +86 18209268326

WhatsApp: +86 18209268326

E-mail: info@richtechpm.com

 

 

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