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Industrial Scale Airlift Stainless steel Fermenter Bioreactor

Bio reactor/Fermenter Airlift bioreactor/fermenter Microbial Fermentation Glass Bioreactors Cell Culture Stainless steel bio reactor Microbial Stainless steel fermentation Microbial Stainless steel parallel fermenter Microbial fermenter Microbial/cell culture SS fermenter

Airlift Bioreactors
RICH SMART airlift fermenter & bioreactor is a gas-liquid bioreactor based on the principle of ventilation pipes, without any mechanical stirring.

Bio reactor/Fermenter Airlift bioreactor/fermenter Microbial Fermentation Glass Bioreactors Cell Culture Stainless steel bio reactor Microbial Stainless steel fermentation Microbial Stainless steel parallel fermenter Microbial fermenter Microbial/cell culture SS fermenter

    Specification of Industrial Scale  Airlift Stainless steel Fermenter Bioreactor  

    Item

    Specification

    Total volume

    5L~1000L,5000L,50KL etc.

    Working volume

    30%~70%

    Stirring system

    Air flow stirring

    Sterilization

    On-site sterilization

    Clean

    Clean in place by spray ball

    Aeriation control

    Manual control by rotor meter (standard)
    Auto control by mass flow meter(optional)

    Feeding

    Automatically feeding by fixed peristaltic pump (standard)
    Variable speed peristaltic pump(optional)

    Anti-foam control

    Automatically add antifoam by peristaltic pump

    Temperature control

    Auto-control, electric heating range: water source add 5℃ to 70℃

    PH control

    2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)

    DO control

    0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

    Sampling

    Sampling valve, can sterilization separately, manual

    Harvest

    Zero dead zone bottom valve(Gemu/Burket,Germany), can sterilization separately, manual/auto

    Lid lift system

    30L-500L have lid lift system, 700-1000L have human hole.

    Pressure

    Auto control, BD Germany pressure transmitter

    Exhaust

    Have condenser before exhaust, control by diagram valve / Proportional control valve.

    Control parameters

    10in touch screen , Siemens PLC control system with control parameters (stirring, pH, DO, temperature, feeding, gas etc.), data
    analysis, data logging, data output and printing, overrun alarm, language switching and other functions

    Optional configuration

    O2/N2/CO2 gas control, Level sensor, OD sensor, Turbidity sensor, ORP sensor, Weight system, Live cell sensor, Light etc

    Total volume

    5L~1000L,5000L,50KL etc.

    Working volume

    30%~70%

    Stirring system

    Air flow stirring

    Sterilization

    On-site sterilization

    Clean

    Clean in place by spray ball

    Aeriation control

    Manual control by rotor meter (standard)
    Auto control by mass flow meter(optional)

    Feeding

    Automatically feeding by fixed peristaltic pump (standard)
    Variable speed peristaltic pump(optional)

    Anti-foam control

    Automatically add antifoam by peristaltic pump

    Temperature control

    Auto-control, electric heating range: water source add 5℃ to 70℃

    PH control

    2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)

    DO control

    0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

    Sampling

    Sampling valve, can sterilization separately, manual




  • Parameters

    Specification of Industrial Scale  Airlift Stainless steel Fermenter Bioreactor  

    Item

    Specification

    Total volume

    5L~1000L,5000L,50KL etc.

    Working volume

    30%~70%

    Stirring system

    Air flow stirring

    Sterilization

    On-site sterilization

    Clean

    Clean in place by spray ball

    Aeriation control

    Manual control by rotor meter (standard)
    Auto control by mass flow meter(optional)

    Feeding

    Automatically feeding by fixed peristaltic pump (standard)
    Variable speed peristaltic pump(optional)

    Anti-foam control

    Automatically add antifoam by peristaltic pump

    Temperature control

    Auto-control, electric heating range: water source add 5℃ to 70℃

    PH control

    2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)

    DO control

    0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

    Sampling

    Sampling valve, can sterilization separately, manual

    Harvest

    Zero dead zone bottom valve(Gemu/Burket,Germany), can sterilization separately, manual/auto

    Lid lift system

    30L-500L have lid lift system, 700-1000L have human hole.

    Pressure

    Auto control, BD Germany pressure transmitter

    Exhaust

    Have condenser before exhaust, control by diagram valve / Proportional control valve.

    Control parameters

    10in touch screen , Siemens PLC control system with control parameters (stirring, pH, DO, temperature, feeding, gas etc.), data
    analysis, data logging, data output and printing, overrun alarm, language switching and other functions

    Optional configuration

    O2/N2/CO2 gas control, Level sensor, OD sensor, Turbidity sensor, ORP sensor, Weight system, Live cell sensor, Light etc

    Total volume

    5L~1000L,5000L,50KL etc.

    Working volume

    30%~70%

    Stirring system

    Air flow stirring

    Sterilization

    On-site sterilization

    Clean

    Clean in place by spray ball

    Aeriation control

    Manual control by rotor meter (standard)
    Auto control by mass flow meter(optional)

    Feeding

    Automatically feeding by fixed peristaltic pump (standard)
    Variable speed peristaltic pump(optional)

    Anti-foam control

    Automatically add antifoam by peristaltic pump

    Temperature control

    Auto-control, electric heating range: water source add 5℃ to 70℃

    PH control

    2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)

    DO control

    0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

    Sampling

    Sampling valve, can sterilization separately, manual




Industrial Scale  Airlift Stainless steel Fermenter Bioreactor  

RICH SMART airlift fermenter & bioreactor is a gas-liquid bioreactor based on the principle of ventilation pipes, without any mechanical stirring.

 

Types of Industrial Scale  Airlift Stainless steel Fermenter Bioreactor  

As for the internal loop airlift bioreactors, compressed air is used for aeration and agitation. The turbulence caused by the gas/fluid flow ensures adequate mixing of the liquid.  The gas used for agitation can act to either side, introduce new molecules to the mixture inside the bioreactor, or remove specific metabolic molecules produced by microorganisms.

 

*Single stage type                                     *Multiple stage type


 

Airlift Bioreactor Diagram

An airlift bioreactor works by stirring cultured substance using gas. Air/Gas is fed through a sparger ring into the bottom of a concentric tube, which directs the circulation of both air bubbles and liquid. At the top of the bioreactor, there is a gas separator to remove gaseous substances. Air bubbles flow upwards within the central draft tube; some of these bubbles coalesce at the top of the column and exit, while others follow the degassed liquid and circulate downward from the area outside the draft tube.

 

Advantages of  Industrial Scale  Airlift Stainless steel Fermenter Bioreactor  

Efficient gas-liquid dispersion with low power consumption

Improved fluidization characteristics

Low shear rate (have homogenous shear and stress forces throughout the entire bioreactor)

Excellent liquid-solid and gas-liquid mass transfer

 

Airlift Bioreactor Vessels

Volume: 200L - 700L, with 70-85% working volume

Material: Tank SUS316L, jacket SUS304 (polishing better than Ra 0.4 um)

Ratio: Diameter to height, 1: 5

 

Design Pressure: Tank 0.3Mpa, Jacket 0.4Mpa

Ports: 5 x sensor port, 2 x gas supply port (ring sparger), 1 x Inoculating port, 1 x Sampling port, 5 x Filling port, other spare ports

Sterilization: SIP online steam sterilization

Sparge: SS316L ring sparger in the bottom

Seal: Mechanical drive or mechanical seal

Options: Storage bottles, vessel passivation, custom port, cover lifting, etc.

 

Choose Your Controller

The airlift bioreactor controller can be customized with RS series controller, matching with the special airlift bioreactor vessel.

 

Applications of Airlift Bioreactor

Ideal for culturing cells that are too sensitive to the shear stress and heat generation caused by the mechanical agitation.

 

Pallet form fermentation; immobilized enzyme reactions.

 

SCP production from methanol as carbon substrate.

 

Typically, airlift bioreactors are used when the desired reactants and/or final products are in a gaseous state and for aerobic cell cultures.

Specification of Industrial Scale  Airlift Stainless steel Fermenter Bioreactor  

Item

Specification

Total volume

5L~1000L,5000L,50KL etc.

Working volume

30%~70%

Stirring system

Air flow stirring

Sterilization

On-site sterilization

Clean

Clean in place by spray ball

Aeriation control

Manual control by rotor meter (standard)
Auto control by mass flow meter(optional)

Feeding

Automatically feeding by fixed peristaltic pump (standard)
Variable speed peristaltic pump(optional)

Anti-foam control

Automatically add antifoam by peristaltic pump

Temperature control

Auto-control, electric heating range: water source add 5℃ to 70℃

PH control

2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)

DO control

0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

Sampling

Sampling valve, can sterilization separately, manual

Harvest

Zero dead zone bottom valve(Gemu/Burket,Germany), can sterilization separately, manual/auto

Lid lift system

30L-500L have lid lift system, 700-1000L have human hole.

Pressure

Auto control, BD Germany pressure transmitter

Exhaust

Have condenser before exhaust, control by diagram valve / Proportional control valve.

Control parameters

10in touch screen , Siemens PLC control system with control parameters (stirring, pH, DO, temperature, feeding, gas etc.), data
analysis, data logging, data output and printing, overrun alarm, language switching and other functions

Optional configuration

O2/N2/CO2 gas control, Level sensor, OD sensor, Turbidity sensor, ORP sensor, Weight system, Live cell sensor, Light etc

Total volume

5L~1000L,5000L,50KL etc.

Working volume

30%~70%

Stirring system

Air flow stirring

Sterilization

On-site sterilization

Clean

Clean in place by spray ball

Aeriation control

Manual control by rotor meter (standard)
Auto control by mass flow meter(optional)

Feeding

Automatically feeding by fixed peristaltic pump (standard)
Variable speed peristaltic pump(optional)

Anti-foam control

Automatically add antifoam by peristaltic pump

Temperature control

Auto-control, electric heating range: water source add 5℃ to 70℃

PH control

2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)

DO control

0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

Sampling

Sampling valve, can sterilization separately, manual






Industrial Scale Airlift Stainless steel Fermenter Bioreactor
Airlift Bioreactors
RICH SMART airlift fermenter & bioreactor is a gas-liquid bioreactor based on the principle of ventilation pipes, without any mechanical stirring.
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XI'AN RICH SMART TECHNOLOGY CO.,LTD

 Address: Zhangba East Road, Yanta District, Xi’an, China.China
Tel: +86 18209268326

WhatsApp: +86 18209268326

E-mail: info@richtechpm.com

 

 

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